On the one hand is the hydrophilic group renowned as the head group which then becomes the basis of species classification of phospholipids, such as phosphatidylcholine (PC), phosphatidyletanolamine (PE), and phosphatidylserine (PS). They are amphiphilic molecules which usually built by glycerol backbone with two different polarity groups attached to it. Phospholipids are major constituent of cellular membrane hence they have excellent biocompability. It had high encapsulation efficiency and addition of cholesterol to the liposome membrane only slightly reduced the efficiency. CocoPEs showed great potency as encapsulation material. All of CocoPEs liposomes encapsulation efficiency with cholesterol concentration up to 30% were above 80%. The temperature (Tp) was at 25.29☌ for changing from planar-shaped gel to rippling phase, 32.62☌ (Tm) for major transition from gel to liquid crystal, and 65.53☌ (Th) from liquid crystal to hexagonal phase. planar-shape gel phase, rippling phase, liquid crystal phase and hexagonal phase. At least four different phases were identified on CocoPEs i.e. ![]() The fatty acyl chains of the species were capric, linoleic, oleic, stearic and arachidic acyl chains. ![]() At least 15 species were found in coconut phosphatidylethanolamine. The purpose of this study was to isolate the ethanolamine species of coconut phospholipid and to investigate their potency as drug delivery system by using it to encapsulate vitamin C. The study consisted of two stages: the first stage was isolation and characterization of coconut phosphatidylethanolamine species and the second stage was utilization of coconut phosphatidylethanolamine liposomes to encapsulate vitamin C. A dark brown gel of coconut phosphatidylethanolamine species (CocoPEs) was isolated from dried coconut meat (9.3×10−3%, w/w).
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